Specialty Genes refers to genes that are of particular interest to infectious disease researchers, such as virulence factors, antibiotic resistance genes, drug targets, and human homologs. For each class, reference genes are collected from reputed external databases or manually curated by the PATRIC team and then mapped to their homologs based on sequence similarity using BLASTP. For more details, see Specialty Genes FAQs. We also provide a data summary targeted specifically to Antibiotic Resistance Data.

What do we mean by ...

Antibiotic Resistance:

Antibiotic Resistance refers to the ability of bacteria to develop resistance to antibiotics through gene mutation or acquisition of antibiotic resistance genes. We have integrated and mapped known antibiotic resistance genes from the following sources:

Drug Targets:

Drug Targets refer to the proteins being targeted by known/approved/experimental small molecule drugs. We have integrated and mapped such drug targets from the following sources:

Human Homologs:

Human Homologs refer to the bacterial proteins that share high sequence similarity with human proteins. We have integrated and mapped proteins from Reference Human Genome at NCBI.

Virulence Factors:

Virulence factors refer to the gene products that enable bacteria to establish itself on or within a host organism and enhance its potential to cause disease. We have integrated and mapped virulence factor genes from the following sources:

Find and Analyze Specialty Genes with PATRIC Tools

View Tutorials

  • Data in PATRIC is organized in a similar fashion at various taxonomic levels throughout the website.  Follow along in this Mycobacterium example and see what data is available and where to find it for your favorite organisms/genomes/genes.

  • Find out more about PATRIC data, analysis tools, and functionality in our Frequently Asked Questions.

  • See how to use PATRIC tables and the Table Toolbar including sorting, downloading, analysis tools, creating persistent column customization, and saving items to your workspace.

How Do We Curate, Integrate, and Map Specialty Genes?

How Do We Curate, Integrate, and Map Specialty Genes?